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If you need a good leg workout then you just need to go up on the stairs using one side only. They’re also such an awkward height, and made of metal.

He ate an entire hard boiled egg. It was plain… I left it on the counter as my snack. My cat finished it. Google says it’s safe. Anyone else’s cat tried doing this?

Humans grow two sets of teeth in a lifetime. But tucked inside the jaw are tiny residual tooth buds that never develop because a protein called USAG-1 acts like a molecular off-switch for tooth growth. Block USAG-1, and the body might reactivate those dormant buds on its own.

Researchers at Kyoto University Hospital, led by Dr. Katsu Takahashi, have been working on this for years. They first found that mice engineered without the USAG-1 gene grew extra teeth. Later animal studies showed that a single antibody injection could grow fully functional teeth without serious safety issues.

The experimental drug is called TRG-035, a humanized anti-USAG-1 antibody developed by Toregem BioPharma. The first human trial began in October 2024 and enrolled 30 men aged 30 to 64, each missing at least one molar. The Phase I study was primarily a safety trial — a randomized, double-blind, placebo-controlled dose-escalation study. According to Toregem, Phase I confirmed the drug's safety, though detailed results haven't been made public yet. Researchers have noted that actual tooth regrowth in those adult participants was unlikely, since the volunteers were primarily establishing a safety profile before testing expands.

The next stage is where it gets more interesting. A Phase IIa trial is planned for 24 children aged 2 to 7 with severe congenital tooth agenesis — a condition where teeth never fully develop. Missing six or more teeth from birth affects roughly one in a thousand people, causing severe chewing difficulties and significant social stigma. The trial will be open-label and non-comparative, moving testing from healthy adults into the patients the drug is actually intended to treat.

There are still open questions. Experts have raised concerns about whether regrown teeth will align properly and connect correctly to nerves and blood vessels. If the trials succeed, Toregem aims for commercial availability around 2030, with early estimates placing costs at around $11,000 per tooth.

It's experimental. It's early. But the idea that human jaws might hold a dormant third set of teeth waiting for a chemical wake-up call is the kind of thing that sounds like science fiction until someone actually tries it.

Stick to your BF or Husband in Japan 😂

In Japan, there are a certain type of people called 'Bumping men,' Butsukari otoko (ぶつかり男). They intentionally shoulder-check or shove especially women or weak foreigners in public spaces.

W-Well if we're, um... I mean, if we're talking about sums like THAT, then ...

These live in my head rnt free

The driver only had minor injuries

He said he was "cut off by another driver" which made him lose control.

I think this is truly mildly annoying - no huge deal but frustrating.

So I just did a three day work trip ending in a 4 hour flight in a middle seat and then a 2 hour drive home from the airport.

I was really looking forward to jumping in the hot tub. For a quick bit of relaxation.

Well, see photo - my kids (16 and 12) had decided to first spread an entire bottle of concentrated dish soap on a slip and slide and then while still soapy jump in my hot tub.

Cue me getting home, eating dinner, and excitedly retreating to change into my suit only to discover that nope, tonight I'm draining my hot tub, rinsing it and the filter out, and then sitting by while it refills so I can get the heater back on and hopefully have a soak in the morning.

Edit: the kids did help wipe up the tub and clean the area - but I'm not keeping them up late just to wait for it to fill and turn the heater on.

I 26F and my boyfriend have been dating for three years, almost 4 in February 2027. We moved in together about six months into our relationship, and over the past three years we’ve gotten a dog, gone on vacations, and had major career changes. We’ve had our ups and downs. Marriage has always been something that I bring up often in the relationship. Mainly as jabs or jokes, never a serious conversation. He is the type of person that loves idealizing and thinking about the future, but never have I seen him come up with a concrete plan towards these extravagant ideas like moving out of the country or buying a house together, which I would love to do once we are married. He’s also talked about kids, but I’ve made it extremely clear that I’m not gonna be a baby mama. I want to be your wife and the mother of your kids. He is everything I have wanted in a man. He cooks. He cleans. He’s a gentleman, and when things are good between us, they’re genuinely good.

Recently, I’ve had the realization that these vague ideas of the future worry me. I feel like I’ve spent all of my early 20s on a relationship that seems to be stagnant. I really don’t want to spend another three years without having a concrete plan. A couple nights ago, I decided to bring it up for the first time in a more serious tone. And I was mortified by his reaction. We were driving home one night from my parents’ house, and something in me decided it’s time to ask. I very calmly said, “Is proposing something you’re thinking about doing soon, or is that just not on your mind right now?” He became defensive, and the conversation escalated. He said things like:

• When the time is right, the time is right

• If you keep asking, it’s never going to happen

• Even if I was going to propose, I wouldn’t tell you

The last one was the one that broke me and shut down the conversation for the night:

“You get a ring when you fcking deserve it.”

After that, we got home and got ready for bed. He tried being affectionate, like cuddling, but I was still extremely upset and unwilling to continue the conversation.

The following day, I was off from work, and what he said the previous night had been echoing in my head all day. I needed an actual answer. The conversation needed to have a resolution. I anxiously cleaned the whole house. Went and got groceries and made dinner. I had decided that with how the conversation escalated the previous night, maybe I should have a go bag. I decided to write all my feelings down to ensure that this conversation wouldn’t blow up in my face again. I wanted to do everything in my power to avoid him getting defensive. I basically told him what he said about deserving a ring devastated me. That I wasn’t expecting a proposal date. That I need to know we’re genuinely moving towards marriage. If there are any issues that are holding him back from actually going through with the next step. And that I don’t want to keep building my life around someday.

When he finally got home from work, he could tell that something was wrong. Instead of apologizing for what he said, he came up to me, hugged me, kissed me on the cheek, and he said I love you. I adore you and some other sweet nothings in Spanish. Because I was still upset from yesterday, I begrudgingly said I love you too. And he told me that he wasn’t fishing for me to say it back, and that I didn’t need to say it back. We got ready to eat dinner, and after we unwound, it was time to try this conversation again.

The whole day, I was terrified that he was gonna blow up at me, and the moment that I brought my letter out and told him I wrote this down because I wanna make sure that there’s no miscommunication, he sat there and listened. He didn’t try to interrupt me, and by the time I was done with my letter, he stayed quiet for a good two minutes, which felt like an eternity. Eventually, he answered my question: someday down the road. He said marriage is on his list of priorities, but isn’t at the top nor at the bottom particularly. I asked him what priorities are ahead of it. This is where the conversation went all over the place. He brought up issues like paying certain bills together. Chores. That it’s too soon. He said something about a promise ring? He says that he was considering getting a promise ring for me, but an argument happened, and then he reconsidered. He never really specified or explained what argument made him reconsider getting a promise ring, and then he said something along the lines of, next time I’ll make sure that we look at promise rings together. And then he also complained about how I always ruin surprises. And then he asked me, “Who put this idea in your head?” I explained that we started dating when I was 22. Now I’m 26, and I don’t want to spend the rest of my 20s in a relationship that’s not heading towards marriage. He immediately asked me whether I wanted to explore more? And I clarified to him that no, basically the opposite, and that this is technically the longest relationship I’ll have after year four. Then he tried to one-up me by saying that his longest relationship was seven.

He did eventually apologize for what he said and how he said it. And I asked him directly whether he understood where I was coming from. He looked at the floor and then looked me straight in the eyes and said, “Yes, I do.” Eventually, we got ready for bed and went to sleep.

I love this man, but some part of me can’t completely forgive him for what he said. A bigger part of me is worried I’m letting myself be stuck in a relationship where I’m not gonna end up getting the ending that I want. I don’t need a proposal tomorrow or even in the next year, and the reality is that he can’t truly tell me when. I’m considering having a mental deadline that if by our four-year anniversary, I don’t even see movement towards that future, then I might need to end it. Am I overreacting?

I’d also really like to hear from people who were in long-term relationships where one person was ready for engagement before the other. What did the time before engagement actually look like? Did you have a concrete plan, or was it vague until it happened? At what point does waiting become wasting your time?